Singles
2010 Karshi Challenger
Champion	Blaž Kavčič
Runner-up	Michael Venus
Score	7–6(6), 7–6(5)

Rainer Eitzinger was the champion in 2009, but he decided to not compete this year.
Blaž Kavčič won the final against Michael Venus 7–6(6), 7–6(5).

Seeds

Draw

Finals

	Semifinals							Final
	1	Blaž Kavčič	6	7
	Q	Vishnu Vardhan	3	65
								1	Blaž Kavčič	7	7
								Q	Michael Venus	66	65
		Yang Tsung-hua	4	3
	Q	Michael Venus	6	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	B Kavčič	7	6
	Q	S Groth	63	3				1	B Kavčič	6	6
		Z Zhang	3						Z Zhang	3	3
		M Ledovskikh	0	r											1	B Kavčič	3	6	6
		V Rudnev	6	7											8	C Poch-Gradin	6	3	2
	WC	V Uzakov	3	5					V Rudnev	3	3
	WC	T Ismailov	2	2				8	C Poch-Gradin	6	6
	8	C Poch-Gradin	6	6																		1	B Kavčič	6	7
	4	M Semjan	6	6																		Q	V Vardhan	3	65
	WC	M Inoyatov	4	1				4	M Semjan	6	2
		A Weintraub	6	6					A Weintraub	0	1	r
		M Elgin	3	4											4	M Semjan	7	3	68
	Q	V Vardhan	6	6											Q	V Vardhan	5	6	7
		H Moriya	1	4				Q	V Vardhan	4	6	6
		D Blömke	6	3	3			5	A Kumantsov	6	4	3
	5	A Kumantsov	4	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	A Juška	6	7
	WC	A Saidmukhamedov	3	5				6	A Juška	2	r
	Q	A Smirnov	64	6	3				M Mečíř Jr.	4
		M Mečíř Jr.	7	4	6											M Mečíř Jr.	3	4
		T-h Yang	6	6												T-h Yang	6	6
		J-M Valverde	3	0					T-h Yang	6	3	6
		L Walter	6	3	2			3	A Martin	2	6	1
	3	A Martin	3	6	6																		T-h Yang	4	3
	7	J Minář	6	6																		Q	M Venus	6	6
		W-s Jun	1	4				7	J Minář	6	2	6
		L Grigelis	3	4					J Statham	3	6	4
		J Statham	6	6											7	J Minář	7	5	61
		B Pašanski	3	7	4										Q	M Venus	69	7	7
	Q	M Venus	6	63	6			Q	M Venus	6	7
		J Zopp	3	3				2	K Kravchuk	1	65
	2	K Kravchuk	6	6

References

• Main draw
• Qualifying singles