Singles
2016 Città di Caltanissetta
Champion	Paolo Lorenzi
Runner-up	Matteo Donati
Score	6–3, 4–6, 7–6(9–7)

Elias Ymer was the defending champion but lost in the second round to Alessandro Giannessi.

Paolo Lorenzi won the title after defeating Matteo Donati 6–3, 4–6, 7–6^(9–7) in the final.

Seeds

Draw

Finals

	Semifinals							Final
	1/WC	Paolo Lorenzi	6	7
		Alessandro Giannessi	4	5
								1/WC	Paolo Lorenzi	6	4	79
								WC	Matteo Donati	3	6	67
		Guido Andreozzi	6	5	2
	WC	Matteo Donati	4	7	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1/WC	P Lorenzi	77	6
		FF Silva	64	4				1/WC	P Lorenzi	4	77	6
		L Đere	79	62	6				L Đere	6	64	3
		F Volandri	67	77	2										1/WC	P Lorenzi	6	6
		G Lama	6	6												G Lama	2	4
	Q	F Horanský	3	4					G Lama	6	6
		S Caruso	6	6					S Caruso	2	2
	6	A González	2	4																		1/WC	P Lorenzi	6	7
	3	E Ymer	6	6																			A Giannessi	4	5
		Y Bai	2	3				3	E Ymer	4	4
	Q	N Jarry	6	5	4				A Giannessi	6	6
		A Giannessi	4	7	6											A Giannessi	6	6
		M Tepavac	6	6												M Arévalo	4	1
	Q	Antonio Massara	4	4					M Tepavac	4	3
		M Arévalo	7	6					M Arévalo	6	6
	8	P Krstin	5	1

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	7	D Gimeno Traver	66	65
	WC	Omar Giacalone	78	77				WC	O Giacalone	2	3
		A Ungur	3	7	4				E López Pérez	6	6
		E López Pérez	6	5	6											E López Pérez	2	4
		G Andreozzi	6	6												G Andreozzi	6	6
	Q	S Nagal	2	4					G Andreozzi	3	6	6
	PR	J Reister	6	4	77			PR	J Reister	6	3	3
	4	T de Bakker	3	6	65																		G Andreozzi	6	5	2
	5	S Giraldo	6	6																		WC	M Donati	4	7	6
		L Giustino	4	1				5	S Giraldo	2	6	64
	WC	M Donati	6	5	78			WC	M Donati	6	3	77
		M Zekić	3	7	66										WC	M Donati	6	3	6
		G Clezar	2	6	66										WC	G Quinzi	4	6	4
	WC	G Quinzi	6	1	78			WC	G Quinzi	6	2	6
		A Arnaboldi	5	5				2	F Bagnis	4	6	2
	2	F Bagnis	7	7

References

• Main draw
• Qualifying draw