Men's singles
2016 Claro Open Medellín
Champion	Facundo Bagnis
Runner-up	Caio Zampieri
Score	6–7(3–7), 7–5, 6–2

Paolo Lorenzi was the defending champion but chose not to defend his title.

Facundo Bagnis won the title after defeating Caio Zampieri 6–7^(3–7), 7–5, 6–2 in the final.

Seeds

Draw

Finals

	Semifinals							Final
		Caio Zampieri	3	710	6
	3	Rogério Dutra Silva	6	68	2
									Caio Zampieri	77	5	2
								2	Facundo Bagnis	63	7	6
	5	João Souza	7	2	2
	2	Facundo Bagnis	5	6	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	V Estrella Burgos	65	67
		A Falla	77	79					A Falla	6	77
		A Ghem	6	6					A Ghem	3	63
		Bastián Malla	2	3												A Falla	63	77	2
		C Zampieri	6	6												C Zampieri	77	62	6
		C Lindell	3	3					C Zampieri	7	6
	Alt	N Barrientos	2	2				8	A González	5	4
	8	A González	6	6																			C Zampieri	3	710	6
	3	R Dutra Silva	6	6																		3	R Dutra Silva	6	68	2
	LL	B Sant'Anna	4	1				3	R Dutra Silva	77	4	6
		JI Londero	6	69	5				F Mena	64	6	2
		F Mena	3	711	7										3	R Dutra Silva	68	6	6
		E Struvay	6	6												E Struvay	710	3	2
	Alt	J Pereira	3	4					E Struvay	6	77
	Q	F Romboli	6	65	66			7	N Kicker	4	65
	7	N Kicker	3	77	78

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	5	J Souza	65	6	6
	WC	Gregorio Cordonnier	77	3	2			5	J Souza	6	6
	WC	DE Galán	4	3					A El Mihdawy	2	3
		A El Mihdawy	6	6											5	J Souza	6	7
		G Lama	0r													J Hernández	0	5
		J Hernández	0						J Hernández	6	4	6
	Q	O Luz	4	6	3			4	R Olivo	3	6	4
	4	R Olivo	6	4	6																	5	J Souza	7	2	2
	6	S Giraldo	6	6																		2	F Bagnis	5	6	6
	WC	Felipe Mantilla	1	2				6	S Giraldo	6	6
	Q	N Santos	4	6	6			Q	N Santos	3	3
	WC	Sergio Luis Hernández Ramírez	6	2	1										6	S Giraldo	3	6	4
	Q	M Zormann	6	2	6										2	F Bagnis	6	2	6
		A Collarini	3	6	4			Q	M Zormann	3	4
		G Escobar	6	3	2			2	F Bagnis	6	6
	2	F Bagnis	3	6	6

References

• Main Draw
• Qualifying Draw