Singles
2016 Milex Open
Champion	Guido Andreozzi
Runner-up	Nicolás Kicker
Score	6–0 , 6–4

Damir Džumhur was the defending champion, but chose to participate in the 2016 Memphis Open instead .

Guido Andreozzi won the title, defeating Nicolás Kicker 6–0, 6–4 in the final .

Seeds

Draw

Finals

	Semifinals							Final
		Jozef Kovalík	5	4
		Guido Andreozzi	7	6
									Guido Andreozzi	6	6
									Nicolás Kicker	0	4
		Mathias Bourgue	4	5
		Nicolás Kicker	6	7

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	V Estrella Burgos	6	6
	Q	G Lama	3	4				1	V Estrella Burgos	3	2
		J Kovalík	7	77					J Kovalík	6	6
	Q	P Riba	5	65												J Kovalík	78	6
		C Hemery	6	6											5	A Martin	66	3
		J Eysseric	4	2					C Hemery	4	65
		O Roca Batalla	4	4				5	A Martin	6	77
	5	A Martin	6	6																			J Kovalík	5	4
	3	G Melzer	77	6																			G Andreozzi	7	6
	WC	N Jarry	63	3				3	G Melzer	3	6	2
		G Andreozzi	6	6					G Andreozzi	6	4	6
		J Samper-Montaña	0	3												G Andreozzi	6	6
	Q	R Quiroz	6	4	6											M Chazal	1	1
	WC	E Gómez	1	6	3			Q	R Quiroz	3	5
		M Chazal	64	6	6				M Chazal	6	7
	7	A Ghem	77	4	4

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	8/Alt	J Souza	6	5	6
		G Lapentti	4	7	4			8/Alt	J Souza	1	64
		M Bourgue	6	7					M Bourgue	6	77
	WC	J Olivares	3	5												M Bourgue	1	6	6
		G Naso	6	6											4	R Carballés Baena	6	4	4
		B Trinker	1	1					G Naso	6	3	62
	WC	N Hardt	1	0				4	R Carballés Baena	4	6	77
	4	R Carballés Baena	6	6																			M Bourgue	4	5
	6	A González	63	6	3																		N Kicker	6	7
		J Hernández-Fernández	77	4	6				J Hernández-Fernández	3	1
		N Kicker	6	6					N Kicker	6	6
	Q	D King	2	1												N Kicker	6	3	6
	Alt	F Škugor	6	0	6											A Giannessi	4	6	2
		R Ramírez Hidalgo	4	6	3			Alt	F Škugor	60	62
		A Giannessi	6	6					A Giannessi	77	77
	2	H Zeballos	1	3

References

• Singles Draw
• Qualifying Draw