Singles
2018 Cary Challenger
Champion	James Duckworth
Runner-up	Reilly Opelka
Score	7–6(7–4), 6–3

Kevin King was the defending champion but lost in the first round to James Duckworth.

Duckworth won the title after defeating Reilly Opelka 7–6^(7–4), 6–3 in the final.

Seeds

Draw

Finals

	Semifinals							Final
	5	Bjorn Fratangelo	3	4
	Q	James Duckworth	6	6
								Q	James Duckworth	77	6
								4	Reilly Opelka	64	3
	4	Reilly Opelka	6	6
		Kaichi Uchida	3	4

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	P Polansky	3	4
		A González	6	6					A González	4	6	6
		M Ymer	6	2	77				M Ymer	6	3	4
		D Pérez Sanz	2	6	62											A González	77	5	4
		M Krueger	3	77	3										5	B Fratangelo	65	7	6
		C Eubanks	6	63	6				C Eubanks	4	4
	WC	A Galarneau	4	3				5	B Fratangelo	6	6
	5	B Fratangelo	6	6																		5	B Fratangelo	3	4
	3	M Arévalo	6	6																		Q	J Duckworth	6	6
	Q	J. J. Wolf	3	3				3	M Arévalo	63	5
	WC	S Korda	63	4				Q	J De Loore	77	7
	Q	J De Loore	77	6											Q	J De Loore	3	63
	Q	Evan Song	6	6											Q	J Duckworth	6	77
	WC	Nick Stachowiak	3	2				Q	E Song	3	64
	Q	J Duckworth	4	6	6			Q	J Duckworth	6	77
	6	K King	6	4	3

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	7	A Popyrin	6	6
		JC Aragone	3	4				7	A Popyrin	77	65	63
		R Ortega Olmedo	6	5	1				D Köpfer	65	77	77
		D Köpfer	3	7	6											D Köpfer	64	4
		J Choinski	77	2	1										4	R Opelka	77	6
		D Young	64	6	6				D Young	1	65
		E Escobedo	611	4				4	R Opelka	6	77
	4	R Opelka	713	6																		4	R Opelka	6	6
	8	M Banes	2	6	3																		K Uchida	3	4
		E King	6	1	6				E King	4	3
		R Cid Subervi	3	1					K Uchida	6	6
		K Uchida	6	6												K Uchida	6	6
	WC	W Blumberg	65	6	0											J Hernández-Fernández	4	3
		A Harris	77	3	0r			WC	W Blumberg	4	3
		J Hernández-Fernández	6	6					J Hernández-Fernández	6	6
	2	E Ymer	3	4

References

• Main Draw
• Qualifying Draw