Singles
2018 Karshi Challenger
Champion	Egor Gerasimov
Runner-up	Sergey Betov
Score	7–6(7–3), 2–0 ret.

Egor Gerasimov was the defending champion and successfully defended his title.

Gerasimov won the title after Sergey Betov retired trailing 6–7^(3–7), 0–2 in the final.

Seeds

Draw

Finals

	Semifinals							Final
		Carlos Boluda-Purkiss	63	1
	Q	Sergey Betov	77	6
								Q	Sergey Betov	63	0r
								3	Egor Gerasimov	77	2
	3	Egor Gerasimov	77	77
		Cem İlkel	64	64

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	H Hurkacz	66	2r
		M Vilella Martínez	78	5					M Vilella Martínez	1	5
		K Kravchuk	63	3				WC	K Sultanov	6	7
	WC	K Sultanov	77	6											WC	K Sultanov	63	4
		E Tyurnev	5	6	2											C Boluda-Purkiss	77	6
		Carlos Boluda-Purkiss	7	3	6				C Boluda-Purkiss	6	5	79
		A Bega	4	4				8	T-h Yang	4	7	67
	8	T-h Yang	6	6																			C Boluda-Purkiss	63	1
	4	U Ignatik	6	6																		Q	S Betov	77	6
	WC	S Fomin	3	3				4	U Ignatik	6	6
		K Uchida	1	6	6				K Uchida	3	3
		H Moriya	6	2	3										4	U Ignatik	3	61
	WC	J Karimov	64	3											Q	S Betov	6	77
	Q	S Betov	77	6				Q	S Betov	6	4	77
	Q	Shuichi Sekiguchi	1	5				7	A Šetkić	4	6	64
	7	A Šetkić	6	7

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	L Harris	77	1	6
		I Gakhov	65	6	3			6	L Harris	3	77	6
		R Ortega Olmedo	77	6					R Ortega Olmedo	6	64	3
	Q	T Lamasine	63	4											6	L Harris	1	6	3
		T Gabashvili	6	6											3	E Gerasimov	6	3	6
		JC Aragone	2	4					T Gabashvili	4	65
	WC	F Dustov	3	4				3	E Gerasimov	6	77
	3	E Gerasimov	6	6																		3	E Gerasimov	77	77
	5	A Nedovyesov	77	7																			C İlkel	64	64
		A Basso	65	5				5	A Nedovyesov	6	3	0r
		C İlkel	6	77					C İlkel	3	6	4
		Jared Hiltzik	2	64												C İlkel	3	6	6
		S Fayziev	6	2	64										Q	S Mukund	6	2	3
	Q	S Mukund	4	6	77			Q	S Mukund	6	0	6
		R Safiullin	4	2				2	N Milojević	3	6	2
	2	N Milojević	6	6

References

• Main Draw
• Qualifying Draw