Singles
2018 Monterrey Challenger
Champion	David Ferrer
Runner-up	Ivo Karlović
Score	6–3, 6–4

Maximilian Marterer was the defending champion but chose not to defend his title.

David Ferrer won the title after defeating Ivo Karlović 6–3, 6–4 in the final.

Seeds

Draw

Finals

	Semifinals							Final
		Ernesto Escobedo
	6	David Ferrer	w/o
								6	David Ferrer	6	6
								5	Ivo Karlović	3	4
	5	Ivo Karlović	66	6	77
	PR	Santiago Giraldo	78	4	63

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	M Granollers	6	6
	Q	Harrison Adams	4	4				1	M Granollers	65	77	7
		R Quiroz	68	6	7				R Quiroz	77	63	5
		M Arévalo	710	3	5										1	M Granollers	65	64
		M Valkusz	0	3												E Escobedo	77	77
		E Escobedo	6	6					E Escobedo	5	6	6
		P Krstin	6	64	3			8	P Martínez	7	4	3
	8	P Martínez	1	77	6																		E Escobedo
	3	P Lorenzi	5	3																		6	D Ferrer	w/o
	WC	J Melzer	7	6				WC	J Melzer	6	64	3
		S Ofner	6	6					S Ofner	3	77	6
		M Vilella Martínez	1	2												S Ofner	3	4
		K King	4	6	4										6	D Ferrer	6	6
		R Cid Subervi	6	2	6				R Cid Subervi	2	77	2
		T Kokkinakis	1	3				6	D Ferrer	6	64	6
	6	D Ferrer	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	5	I Karlović	78	7
		T de Bakker	66	5				5	I Karlović	3	6	77
		S Kozlov	2	4				WC	L Gómez	6	3	64
	WC	L Gómez	6	6											5	I Karlović	6	6
		B Fratangelo	6	6												B Fratangelo	4	3
	WC	G López Villaseñor	3	2					B Fratangelo	6	6
	Q	Z Piros	6	5	77			Q	Z Piros	1	2
	4	A Menéndez Maceiras	1	7	64																	5	I Karlović	66	6	77
	7	G Melzer	7	6																		PR	S Giraldo	78	4	63
		E King	5	3				7	G Melzer	77	4	6
		N Serdarušić	6	6					N Serdarušić	64	6	3
	WC	V Estrella Burgos	3	1											7	G Melzer	77	5	3
	Q	Pavel Krainik	4	4											PR	S Giraldo	65	7	6
	PR	S Giraldo	6	6				PR	S Giraldo	4	6	6
	Q	G Escobar	6	6				Q	G Escobar	6	2	4
	LL	S Bangoura	4	3

References

• Main Draw
• Qualifying Draw