Singles
2018 Morelos Open
Champion	Dennis Novikov
Runner-up	Cristian Garín
Score	6–4, 6–3

Alexander Bublik was the defending champion but chose not to defend his title.

Dennis Novikov won the title after defeating Cristian Garín 6–4, 6–3 in the final.

Seeds

Draw

Finals

	Semifinals							Final
	6/WC	Thanasi Kokkinakis
		Cristian Garín	w/o
									Cristian Garín	4	3
								3	Dennis Novikov	6	6
	3	Dennis Novikov	6	6
	7	Peđa Krstin	1	4

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	A Martin	6	5	7
		R Quiroz	2	7	5			1	A Martin	6	6
		C Eubanks	6	6					C Eubanks	4	2
		N Scholtz	3	4											1	A Martin	6	67	2
		DE Galán	6	0											6/WC	T Kokkinakis	3	79	6
		J Hernández-Fernández	1	0r					DE Galán	64	5
		Carlos Boluda-Purkiss	2	64				6/WC	T Kokkinakis	77	7
	6/WC	T Kokkinakis	6	77																		6/WC	T Kokkinakis
	4	E King	61	6	6																		C Garín	w/o
		R Statham	77	3	3			4	E King	3	64
		M Matosevic	2	4					C Garín	6	77
		C Garín	6	6												C Garín	6	3	6
	WC	L Patiño	0	2											8	D Popko	1	6	1
		A González	6	6					A González	1	3
		S Diez	6	2	2			8	D Popko	6	6
	8	D Popko	4	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	5	M Arévalo	4	7	66
	Q	Sebastian Fanselow	6	5	78			Q	S Fanselow	4	4
		A Sarkissian	6	6					A Sarkissian	6	6
	WC	M Sánchez	4	4												A Sarkissian	1	64
		J Choinski	4	3											3	D Novikov	6	77
		A Pavić	6	6					A Pavić	4	67
		R Ortega Olmedo	62	7	4			3	D Novikov	6	79
	3	D Novikov	77	5	6																	3	D Novikov	6	6
	7	P Krstin	6	6																		7	P Krstin	1	4
	WC	T Hank	3	0				7	P Krstin	65	6	6
		A Krajicek	5	0r				Q	R Cid Subervi	77	3	0
	Q	R Cid Subervi	7	1											7	P Krstin	6	6
		M Vilella Martínez	4	6	4										2	K King	4	4
	Q	G López Villaseñor	6	4	6			Q	G López Villaseñor	1	1
	Q	E Gómez	4	3				2	K King	6	6
	2	K King	6	6

References

• Main draw
• Qualifying draw