Singles
2018 Open Città della Disfida
Champion	Marco Trungelliti
Runner-up	Simone Bolelli
Score	2–6, 7–6(7–4), 6–4

Aljaž Bedene was the defending champion but chose not to defend his title.

Marco Trungelliti won the title after defeating Simone Bolelli 2–6, 7–6^(7–4), 6–4 in the final.

Seeds

Draw

Finals

	Semifinals							Final
		Jaume Munar	63	1
	Q	Marco Trungelliti	77	6
								Q	Marco Trungelliti	2	77	6
									Simone Bolelli	6	64	4
	WC	Gian Marco Moroni	4	2
		Simone Bolelli	6	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	M Cecchinato	3	5
		N Milojević	6	7					N Milojević	5	1
		J Munar	77	4	7				J Munar	7	6
		F Auger-Aliassime	64	6	5											J Munar	6	77
	WC	M Donati	2	6	6										WC	M Donati	4	65
		G Andreozzi	6	3	4			WC	M Donati	6	6
		B Bonzi	2	0				5	Y Maden	2	4
	5	Y Maden	6	6																			J Munar	63	1
	3	S Travaglia	4	4																		Q	M Trungelliti	77	6
	Q	M Trungelliti	6	6				Q	M Trungelliti	6	2
	Q	Z Piros	2	1					A Giannessi	3	0r
		A Giannessi	6	6											Q	M Trungelliti	6	6
		S Nagal	6	3	2											G Oliveira	1	3
		G Oliveira	4	6	6				G Oliveira	4	0
		N Kuhn	6						N Kuhn	6	2r
	7	M Granollers	5r

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	M Kližan	6	6
	Q	K Coppejans	4	0				6	M Kližan	4	1r
	Q	D Gimeno Traver	6	77				Q	D Gimeno Traver	6	4
	LL	M Chazal	2	64											Q	D Gimeno Traver	3	4
		A Pavlásek	6	63	66										WC	GM Moroni	6	6
	WC	A Pellegrino	3	77	78			WC	A Pellegrino	4	6	1
	WC	GM Moroni	6	6				WC	GM Moroni	6	4	6
	4	P Sousa	1	4																		WC	GM Moroni	4	2
	9	L Sonego	6	6																			S Bolelli	6	6
		J Domingues	2	4				9	L Sonego	5	3
	LL	O Otte	77	4	1				S Bolelli	7	6
		S Bolelli	61	6	6											S Bolelli	6	1
		V Galović	4	6	6											V Galović	2	0r
		M Safwat	6	3	2				V Galović	6	6
	LL	M Tepavac	6	5	0			2	G Elias	1	2
	2	G Elias	3	7	6

References

• Main Draw
• Qualifying Draw