Teams

League positions of the previous season shown in parentheses (TH: EuroLeague Women title holders; EC: EuroCup Women title holders).

Regular season
ZVVZ USK Praha (1st)	UMMC EkaterinburgTH (1st)
Basket Landes (1st)	Dynamo Kursk (2nd)
BLMA (2nd)	MBA Moscow (3rd)
Sopron Basket (1st)	Perfumerías Avenida (1st)
Reyer Venezia (1st)	Spar Girona (CW, 3rd)
TTT Riga (1st)	Fenerbahçe (1st)
VBW Arka Gdynia (1st)	Galatasaray (2nd)
Qualifying round
Conference 1	Conference 2
KSC Szekszárd (2nd)	Tango Bourges Basket (3rd)
ACS Sepsi SIC (1st)	Beretta Famila Schio (2nd)
Kayseri Basketbol (10th)	Valencia BasketEC (2nd)

Schedule

Draw

The draw was held on 19 August 2021 in Freising, Germany.^[6][7]

Draw rules are as follows.

• A maximum of two clubs from the same country can be in the same Regular Season group for countries that have up to three clubs in total.
• Each group can have a maximum of two countries that are represented by two clubs each.
• If there are exactly two clubs from the same country, those clubs shall be drawn into different groups if possible.

Seed 1	Seed 2	Seed 3	Seed 4
UMMC Ekaterinburg Fenerbahçe	Dynamo Kursk Perfumerías Avenida	ZVVZ USK Praha Sopron Basket	Spar Girona BLMA

Seed 5	Seed 6	Seed 7	Seed 8
TTT Riga Galatasaray	Reyer Venezia Basket Landes	VBW Arka Gdynia MBA Moscow	Qualifier 1 Qualifier 2

Conference 1

Pos	Team	Pld	W	L	PF	PA	PD	Pts	Qualification		SZE	SEP	KAY
1	KSC Szekszárd	2	2	0	143	126	+17	4	Regular season			63–56
2	ACS Sepsi SIC (H)	2	1	1	135	141	−6	3	EuroCup Women				79–78
3	Kayseri Basketbol	2	0	2	148	159	−11	2			70–80

Conference 2

Pos	Team	Pld	W	L	PF	PA	PD	Pts	Qualification		SCH	BOU	VAL
1	Beretta Famila Schio (H)	2	2	0	125	105	+20	4	Regular season			69–57
2	Tango Bourges Basket	2	1	1	132	141	−9	3	EuroCup Women				75–72
3	Valencia Basket	2	0	2	120	131	−11	2			48–56

Group A

Pos	Team	Pld	W	L	PF	PA	PD	Pts	Qualification		EKA	AVE	USK	BLM	TTT	VEN	MBA	SZE
1	UMMC Ekaterinburg	14	14	0	1222	944	+278	28	Excluded			110–102	75–73	108–53	75–60	75–69	104–65	89–52
2	Perfumerías Avenida	14	11	3	1130	978	+152	25	Advance to quarterfinals		67–93		85–75	88–67	72–41	110–69	70–64	96–54
3	ZVVZ USK Praha	14	10	4	1170	900	+270	24			77–90	80–55		89–54	84–64	88–53	92–61	83–56
4	BLMA	14	6	8	959	1078	−119	20			73–92	65–78	75–74		63–54	52–74	86–77	82–57
5	TTT Riga	14	6	8	825	983	−158	20			56–71	51–71	52–103	45–80		71–57	64–59	69–68
6	Umana Reyer Venezia	14	5	9	934	990	−56	19	Transfer to EuroCup Women		67–74	56–71	75–84	79–59	54–62		61–62	80–59
7	MBA Moscow	14	4	10	943	1064	−121	18	Excluded		63–84	69–77	54–79	98–78	61–68	72–75		65–62
8	KSC Szekszárd	14	0	14	855	1101	−246	14	Transfer to EuroCup Women		67–82	84–88	51–89	65–72	65–68	51–65	64–73

Group B

Pos	Team	Pld	W	L	PF	PA	PD	Pts	Qualification		FEN	SOP	SCH	KUR	GIR	LAN	GAL	GDY
1	Fenerbahçe	14	11	3	1108	892	+216	25	Advance to quarterfinals			73–47	82–65	83–58	78–57	65–70	107–62	87–67
2	Sopron Basket	14	8	6	935	897	+38	22			59–82		67–58	79–72	53–68	76–54	73–44	67–40
3	Beretta Famila Schio	14	8	6	1011	966	+45	22			64–60	71–70		64–80	68–76	96–56	76–73	75–61
4	Dynamo Kursk	14	8	6	1038	1021	+17	22	Excluded		57–63	73–77	74–93		92–75	75–57	78–76	86–76
5	Spar Girona	14	7	7	972	977	−5	21	Advance to quarterfinals		71–59	63–68	65–55	66–71		70–78	55–69	80–70
6	Basket Landes	14	7	7	966	1050	−84	21	Transfer to EuroCup Women		76–93	61–52	64–79	78–75	71–80		71–62	79–70
7	Galatasaray	14	5	9	968	1038	−70	19			69–89	67–61	67–80	70–80	80–68	83–64		71–60
8	VBW Arka Gdynia	14	2	12	935	1092	−157	16			70–87	71–86	71–67	64–67	65–78	74–87	76–75

Bracket

	Semifinals				Final
	8 April
	Perfumerías Avenida	69
					10 April
	Sopron Basket	74
					Sopron Basket	60
	8 April
					Fenerbahçe	55
	ZVVZ USK Praha	74
	Fenerbahçe	83
					Third place
					10 April
					Perfumerías Avenida	71
					ZVVZ USK Praha	59

Semifinals

Perfumerías Avenida v Sopron Basket

8 April 2022	Perfumerías Avenida	69–74	Sopron Basket	Istanbul
17:00 (UTC+3)	Scoring by quarter: 13–22, 18–25, 21–17, 17–10
	Pts: Copper 23 Rebs: Copper, Alarie 6 Asts: Rodríguez, Cazorla 3 PIR: Copper 15	Boxscore	Pts: Brooks 27 Rebs: Határ 10 Asts: Williams 6 PIR: Brooks 26	Arena: Ülker Sports and Event Hall Referees: Jelena Tomić (CRO), Beniamino Manuel Attard (ITA), Mihkel Männiste (EST)

ZVVZ USK Praha v Fenerbahçe

8 April 2022	ZVVZ USK Praha	74–83	Fenerbahçe	Istanbul
20:00 (UTC+3)	Scoring by quarter: 23–28, 22–10, 18–21, 11–24
	Pts: Oblak 22 Rebs: Thomas 14 Asts: Thomas 8 PIR: Oblak 24	Boxscore	Pts: Iagupova 24 Rebs: Williams 11 Asts: Iagupova 7 PIR: Iagupova 27	Arena: Ülker Sports and Event Hall Referees: Paulo Marques (POR), Amel Dahra (FRA), Gatis Saliņš (LAT)

Third place game

Perfumerías Avenida v ZVVZ USK Praha

10 April 2022	Perfumerías Avenida	71–59	ZVVZ USK Praha	Istanbul
14:00 (UTC+3)	Scoring by quarter: 12–19, 20–18, 22–9, 17–13
	Pts: Samuelson 25 Rebs: Copper 8 Asts: Copper, Cazorla 5 PIR: Samuelson 28	Boxscore	Pts: Jones 26 Rebs: Thomas 9 Asts: Voráčková 7 PIR: Voráčková, Jones 23	Arena: Ülker Sports and Event Hall Referees: Özlem Yalman (TUR), Jelena Tomić (CRO), Viola Györgyi (ROU)

Final

Sopron Basket v Fenerbahçe

10 April 2022	Sopron Basket	60–55	Fenerbahçe	Istanbul
17:00 (UTC+3)	Scoring by quarter: 16–6, 13–13, 16–19, 15–17
	Pts: Williams 16 Rebs: Brooks 11 Asts: Williams, Fegyverneky 3 PIR: Williams 17	Boxscore	Pts: Iagupova 13 Rebs: Williams 8 Asts: Iagupova 5 PIR: Çakır 12	Arena: Ülker Sports and Event Hall Referees: Paulo Marques (POR), Beniamino Manuel Attard (ITA) Gatis Saliņš (LAT)

2021–22 EuroLeague Women Champions
Sopron Basket First title

EuroLeague Final Four MVP

• Gabby Williams ( Sopron Basket)^[8]

MVP of the Month

Month	Player	Team	Ref.
2021
October	Eva Lisec	Dynamo Kursk	[9]
November	Sandrine Gruda	Beretta Famila Schio	[10]
December	Brionna Jones	ZVVZ USK Praha	[11]
2022
January	Natasha Howard	Dynamo Kursk	[12]
February	Alyssa Thomas	ZVVZ USK Praha	[13]