The acronym AICD may refer to:

• Automated Implantable Cardioverter-Defibrillator
• Amyloid precursor protein Intracellular Cytoplasmic/C-terminal Domain, the smaller cleavage product of APP by gamma-secretase
• Australian Institute of Company Directors, an organisation supporting company directors in Australia
• Activation-induced cell death (AICD), important for maintaining T cell homeostasis of the immune system. Autoreactive T cells undergo apoptosis through AICD both from the thymus and periphery