After You've Gone may refer to:

Music

• "After You've Gone" (song), a 1918 song written by Turner Layton and Henry Creamer
• After You've Gone, an album by Lenny Solomon
• After You've Gone, a 2004 album by Barre Phillips, Tetsu Saitoh, William Parker, and Joëlle Léandre

Television and film

• After You've Gone (TV series), a 2007–2008 British sitcom
• After You've Gone, 1984 UK film starring Adrian Dunbar
• "After You've Gone", an episode of Jake and the Fatman
• "After You've Gone", an episode of True Detective

Literature

• After You've Gone, a 1989 short-story collection by Alice Adams
• After You've Gone, a 2007 novel by Joan Lingard
• After You've Gone: My Life After Maurie Fields, a 1998 book by Val Jellay