Ambucetamide

Ambucetamide
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-(dibutylamino)-2-(4-methoxyphenyl)acetamide;
CAS Number	519-88-0 ;
PubChem CID	10616;
ChemSpider	10171 ;
UNII	131B408RZI;
ChEMBL	ChEMBL2104638 ;
CompTox Dashboard (EPA)	DTXSID4057760 ;
ECHA InfoCard	100.007.527
Chemical and physical data
Formula	C17H28N2O2
Molar mass	292.423 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N)C(c1ccc(OC)cc1)N(CCCC)CCCC;
	InChI InChI=1S/C17H28N2O2/c1-4-6-12-19(13-7-5-2)16(17(18)20)14-8-10-15(21-3)11-9-14/h8-11,16H,4-7,12-13H2,1-3H3,(H2,18,20) ; Key:WUSAVCGXMSWMQM-UHFFFAOYSA-N ;
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Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain. It was discovered in 1953 by Paul Janssen.

References

Hoekstra JB, Fisher DS, Cull KM, Tisch DE, Dickison HL (September 1957). "Studies with a uterine antispasmodic, ambucetamide". Journal of the American Pharmaceutical Association. 46 (9): 564–568. doi:10.1002/jps.3030460915. PMID 13491452.
Pickles VR, Clitheroe HJ (March 1960). "The effects of ambucetamide on human myometrial and other preparations, and its antagonism to the menstrual stimulant". British Journal of Pharmacology and Chemotherapy. 15 (1): 128–30. doi:10.1111/j.1476-5381.1960.tb01220.x. PMC 1481989. PMID 14432761.

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