Apure may refer to:
In Venezuela
- Apure Province (1830 to 1864)
- Apure State
- Alto Apure District
- Apure River
- San Fernando de Apure, a city
In Gran Colombia
- Apure Province (17 July 1823 - 1864)
- Apure Department (1824-1830)
- La Campaña de Apure
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