Argyropolis or Argyroupolis (Greek: Αργυρούπολις, "silver town") can refer to:

• Argyropolis (Thrace), a town of ancient Thrace, now in Turkey
• Gümüşhane in the Pontus (northeastern Turkey)
• Argyroupoli, a southern suburb of Athens, Greece, founded by refugees from Gümüşhane
• Argyroupoli, Rethymno, a village in the Rethymno regional unit, Crete
• Argirópolis, a city proposal by Argentinian statesman Domingo F. Sarmiento to be the capital of the Confederate States del Plata (Argentina, Paraguay and Uruguay)

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