Ayres is a surname. Notable people with the surname include:
- Agnes Ayres (1898–1940), American silent film actor
- Alice Ayres (1859–1885), English nursemaid, honored for rescuing her three nieces from a burning building at the cost of her own life
- Anne Ayres (1816–1886), American Episcopalian nun
- Benjamin Ayres (born 1977) an actor, director, photographer
- Benjamin Ayres (instrument maker) (died c. 1775), an English instrument maker
- Bill Ayres, American radio talk show host, co-founder and executive director of World Hunger Year
- Caroline Ayres (born 1981), English basketball player
- Christopher Ayres (1965–2021), American voice actor
- Clara Ayres (1880–1917), American nurse during the First World War
- Clarence Edwin Ayres (1891–1972), American economist
- David Ayres (born 1977), Canadian ice hockey goaltender
- David Ayres (soldier) (1841–1916), Union Army Medal of Honor recipient
- Ed Ayres (disambiguation), multiple people
- Gary Ayres (born 1960), Australian rules footballer and coach
- Gillian Ayres (1930–2018), British painter
- Greg Ayres (born 1968), American voice actor
- Harry Ayres (footballer) (1920–2002), British footballer
- Harry Ayres (mountaineer) (1912–1987), New Zealand guide and mountaineer
- Helen Ayres, Australian violinist, member of the Seraphim Trio
- Ian Ayres (born 1959), American professor at Yale Law School and Yale School of Management
- Ian Ayres (filmmaker), American filmmaker
- João Maria Correia Ayres de Campos, 1st Count of Ameal (1847–1920), Portuguese humanist, politician and art-collector
- José Márcio Ayres (1954–2003), Brazilian primatologist and conservationist
- Leonard Porter Ayres (1879–1946), American statistician
- Lew Ayres (1908–1996), American actor
- Lewis Ayres, lay Catholic theologian
- Pam Ayres (born 1947), British writer of humorous poetry
- Philip Ayres (poet) (1638–1712), English poet
- Philip Burnard Ayres, British physician and botanist
- Richard Ayres (born 1965), British composer
- Robert Ayres (disambiguation), multiple people
- Romeyn B. Ayres (1825–1888), Union general in the American Civil War
- Rosalind Ayres (born 1946), British actress
- Stuart Ayres (born 1980), Australian politician
- Thomas Ayres (artist) (1816–1858), California gold rush-era artist
- Thomas Ayres (ornithologist) (1828–1913), British-born South African ornithologist
- Thomas E. Ayres (born 1962), American military lawyer
- Vernon Ayres (1908–1968), Canadian ice hockey player
Venâncio de Oliveira Ayres (1841-1885) Brazilian Journalist
- William Orville Ayres (1817–1887), American physician and ichthyologist
See also
- Ayer (surname)
- Edward L. Ayers, American historian and educator
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