Baby Jane may refer to:

Books

• What Ever Happened to Baby Jane (novel), a 1960 novel by Henry Farrell
• Baby Jane, a novel by Finnish writer Sofi Oksanen

Persons

• Baby Jane Holzer (Jane Bruckenfeld, 1940), American actress, and model for Andy Warhol appearing in Soap Opera (1964), Couch (1964), and Camp (1965)
• Juanita Quigley (1931–2017), American actress billed as "Baby Jane" in several early roles

Film, television and video games

• What Ever Happened to Baby Jane (1962 film), a film based on the novel, starring Bette Davis and Joan Crawford
• What Ever Happened to Baby Jane (1991 film), a remake based on the novel, starring Vanessa Redgrave and Lynn Redgrave
• Baby Jane Hudson, a character from the above work
• Baby Jane, a Splicer model in the video games BioShock and BioShock 2

Music

• "Baby Jane", song from Midnight Rave With The Pleazers EP written Dello, Cane
• "Baby Jane" (Rod Stewart song), 1983
• "Baby Jane" (Dr. Feelgood song), 1977
• Baby Jane (EP), an EP by Honey Is Cool
• Baby Jane, Christina Aguilera's alias for the 2006 album Back to Basics