Benign lipoblastomatosis
Other namesEmbryonic lipoma[1]
SpecialtyDermatology

Benign lipoblastomatosis is a tumor consisting of fetal-embryonal adipocytes, frequently confused with a liposarcoma, affecting exclusively infants and young children, with approximately 90% of cases occurring before 3 years of age.[2][3]: 626  The term lipoblastomatosis was first used by Vellios et al. in 1958, at which point the tumor became generally accepted as a distinctive entity.[4][5] Today Diffuse lipoblastoma is the preferred term for lipoblastomatosis.[6][7] The tumor is rare, accounting for less than 1% of all childhood neoplasm,[8] and it has been found to be more common in males than females.[9][8] It often presents as an asymptomatic rapidly enlarging mass, occurring more often in the soft tissues of the extremities.[8][9]

See also

References

  1. ↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ↑ Kumar, A.; Brierley, D.; Hunter, K.D.; Lee, N. (November 2015). "Rapidly-growing buccal mass in a 6-month-old infant". British Journal of Oral and Maxillofacial Surgery. 53 (9): 888–890. doi:10.1016/j.bjoms.2015.07.006. PMID 26250364.
  3. ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  4. ↑ Vellios, F; Baez, J; Shumacker, HB (November 1958). "Lipoblastomatosis: a tumor of fetal fat different from hibernoma; report of a case, with observations on the embryogenesis of human adipose tissue". The American Journal of Pathology. 34 (6): 1149–59. PMC 1934796. PMID 13583102.
  5. ↑ Gammelgaard, Niels; Jørgensen, Karstein; Lund, Claus (July 1983). "Benign Lipoblastoma in the Neck Causing Respiratory Insufficiency". The Laryngoscope. 93 (7): 935–937. doi:10.1288/00005537-198307000-00017. PMID 6865630. S2CID 35331275.
  6. ↑ Robinson, Philip; Vanhoenacker, Filip M. (2017). "Adipocytic Tumors". Imaging of Soft Tissue Tumors: 197–241. doi:10.1007/978-3-319-46679-8_12. ISBN 978-3-319-46677-4.
  7. ↑ Ahlawat, Shivani; M. Fayad, Laura (2020). "Revisiting the WHO classification system of soft tissue tumours: emphasis on advanced magnetic resonance imaging sequences. Part 1". Polish Journal of Radiology. 85 (1): 396–408. doi:10.5114/pjr.2020.98685. PMC 7509695. PMID 32999693.
  8. 1 2 3 Kamal, Achmad Fauzi; Wiratnaya, I. Gde Eka; Hutagalung, Errol Untung; Prasetyo, Marcel; Kodrat, Evelina; Widodo, Wahyu; Effendi, Zuhri; Husodo, Kurniadi (2014-09-15). "Lipoblastoma and Lipoblastomatosis of the Lower Leg". Case Reports in Orthopedics. 2014: 582876. doi:10.1155/2014/582876. PMC 4181785. PMID 25302126.
  9. 1 2 Calobrisi, Stella D.; Garland, Jeffery S.; Esterly, Nancy B. (1998). "Congenital Lipoblastomatosis of the Lower Extremity in a Neonate". Pediatric Dermatology. 15 (3): 210–213. doi:10.1111/j.1525-1470.1998.tb01318.x. PMID 9655318. S2CID 45439781.


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