Bill Nelson (born 1942) is the administrator of NASA and former U.S. senator from Florida.

Bill Nelson may also refer to:

Arts and entertainment

• Bill Nelson (artist) (born 1946), illustrator and sculptor
• Bill Nelson (musician) (born 1948), English singer, guitarist and songwriter
• Bill Nelson (sound engineer) (20th century), American sound engineer
• Billy Nelson (actor) (1903–1973), American actor
• Billy Bass Nelson (born 1951), American musician, member of the P-funk All Stars

Sports

• Bill Nelson (American football) (1948–2010), American football defensive tackle
• Bill Nelson (baseball) (1863–1941), American baseball player
• Bill Nelson (sports coach), Australian swimming coach

Others

• Bill Nelson, murder victim who was killed, cooked and eaten by his wife Omaima Nelson
• Desiré Dubounet or Bill Nelson (born 1951), American alternative medicine promoter

See also

• William Nelson (disambiguation)
• Bill Nelsen (1941–2019), American football player