Caggiano is a surname. Notable people with the surname include:
- Antonio Caggiano (1889–1979), Argentine Roman Catholic cardinal
- Biba Caggiano, Italian-American cookbook author, television chef and restaurateur
- Emanuele Caggiano (1837–1905), Italian sculptor
- Fedele Caggiano (1804–1880), Italian sculptor
- Frank Caggiano (born 1959), American Roman Catholic bishop
- Jeremías Caggiano (born 1983), Argentine football striker
- Pasquale Caggiano (1909–1972), American politician
- Rob Caggiano (born 1976), American guitarist and producer
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