Cape Horn (also Hoorn) is the southernmost headland of Hornos Island at the Drake Passage, sometimes erroneously known as the southernmost point of South America.

Cape Horn may also refer to:

• Cabo de Hornos, Chile, a Chilean commune
• Cape Horn Biosphere Reserve, located in the extreme south of Chile
• Cabo de Hornos National Park, also located in the extreme south of Chile
• Cabo de Hornos, an oceanographic research ship operated by the Chilean Navy
• Cape Horn, the southernmost headland of South America
• Cape Horn, Mendocino County, California
• Cape Horn, Placer County, California
• Cape Horn (Washington), a mountain in Washington state
• Cape Horn Interchange, a major freeway intersection on Highway 1 (the Trans-Canada Highway) in Coquitlam, British Columbia, Canada

See also

• False Cape Horn, the southernmost point of the large islands of the Tierra del Fuego group
• Cape Horner, a captain of a sailing ship which has sailed around Cape Horn
• Cape Froward, the southernmost point on the mainland of the American continent.
• Diego Ramírez Islands, the southernmost point of the American continent (including islands)