Chain of Lakes, Chain O'Lakes, or Chain-O-Lakes is a common name for a series of lakes linked by waterways. Some of these include:

Bodies of water

• Chain of Lakes (Winter Haven), Florida
• Chain O'Lakes and Chain O'Lakes State Park (Illinois), in northeast Illinois
• The Chain of Lakes (Minneapolis) area in Minneapolis, Minnesota
• Chain of Lakes (Michigan)
• Chain of Lakes in Hill County, Montana
• Fulton Chain Lakes, New York
• Chain of Lakes (South Dakota)

Populated places

• Chain-O-Lakes, Indiana, an unincorporated community in St. Joseph County
• Chain-O-Lakes, Missouri, a village in Barry County
• Chain O' Lakes, Wisconsin

Other

• Chain of Lakes Middle School, a public middle school in Windermere, Florida
• Chain of Lakes Park, a baseball stadium in Winter Haven, Florida used by the Cleveland Indians for spring training
• Chain O'Lakes State Park (Indiana), in northeast Indiana