Charlie Harper may refer to:
- Charlie Harper (Two and a Half Men), a fictional character in the CBS sitcom Two and a Half Men
- Charlie Harper (singer) (born 1944), member of the punk rock band U.K. Subs
- Charlie Harper (American football) (born 1944), American football player
See also
- Charley Harper (1922–2007), American Modernist artist
- Charles Harper (disambiguation)
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