Claude is a surname. It may refer to :
- Albert Claude (1899–1983), a Belgian Nobel Prize in Medicine recipient
- Bonivert Claude (born 1945), a Former Bank of Haïti governor
- François Auguste Claude (1858–1938), French astronomer
- Georges Claude (1870–1960), a French engineer, chemist and inventor
- Jean Claude (1619–1687), a French Protestant theologian
- Marcel Claude (born 1957), a Chilean economist, politician, and candidate for President of his country
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