Columbia Center is the tallest skyscraper in Seattle.

Columbia Center may also refer to:

• Columbia Centre, a landmark office building in Bracknell, Berkshire, England
• Columbia Center (Troy), twin towers in Troy, Michigan
• Columbia Center, a shopping mall in Kennewick, Washington
• Columbia Center, Ohio, an unincorporated community
• Columbia Center, New York, a hamlet in Herkimer County, New York

See also

• Columbia Building (disambiguation)