Croce is an Italian surname meaning literally "cross". Notable people with the surname include:

• A. J. Croce (born 1971), American singer-songwriter
• Alberto Croce (born 1944), Italian professional golfer
• Alessandro Croce (1650–1704), Italian prelate
• Andrea Giuseppe Croce (1914–1986), Italian businessman
• Antonio Croce (born 1986) Italian footballer
• Arlene Croce (born 1934), American dance critic
• Baldassare Croce (1558–1628), Italian painter
• Benedetto Croce (1866–1952), Italian philosopher and critic
• Carlo M. Croce (born 1944), Italian-American oncologist
• Carlo Croce (born 1945), Italian yacht racer
• Daniele Croce (born 1982), Italian footballer
• Fabiano Santacroce (born 1986), Italian Brazilian association football player
• Francesco Croce (1696–1773), Italian baroque architect
• Fulvio Croce (1901–1977), Italian lawyer
• Giovanni Croce (1557–1609), Italian composer
• Giovanni Andrea Croce (died 1595), Italian prelate
• Giulio Cesare Croce (1550–1609), Italian playwright
• Ingrid Croce (born 1947), American singer-songwriter and wife of Jim
• Ireneo della Croce (1625–1713), Italian preacher
• Jim Croce (1943–1973), American singer-songwriter
• Luigi Croce (born 1940), Italian yacht racer
• Marcos Croce (1894–1978), Argentine footballer
• Maria Eufrasia della Croce (1597–1676), Italian nun and painter
• Mary Keating Croce (1928–2016), American politician
• Nicolás Emanuel Croce (born 1985), Argentine footballer
• Onofrio de Santa Croce (died 1471), Italian cardinal
• Paola Croce (born 1978), Italian volleyball player
• Pat Croce (born 1954), Italian-American entrepreneur
• Pellegrino Croce (born 1955), Italian rower
• Stefania Croce (born 1970), Italian professional golfer