Cuke may refer to:
- "Cuke", a nickname for Cucumber
 
People with the name Cuke include:
- Michelle Bush-Cuke (born 1961), Caymanian long-distance runner
 - Cuke Barrows (1883–1955), American baseball outfielder
 
See also
- Çükəş, a village in the municipality of Sipiyəpart in the Astara Rayon of Azerbaijan
 - Cucumber (disambiguation)
 - Sea cucumber, a type of echinoderm marine animal
 - Zuke (disambiguation)
 
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