Curtis Jackson or 50 Cent (born 1975), is an American rapper.
Curtis Jackson may also refer to:
- Curtis Jackson (gridiron football) (born 1973), American football wide receiver
- Curtis Jackson (cricketer) (born 1967), Bermudian cricketer
- Curtis "C.J." Jackson, fictional character from the American television series, The White Shadow
- Curtis Jackson, character in American Ninja
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