Ávalos is a Spanish surname. Notable people with the surname include:
- Cristiano Ávalos dos Passos (born 1977), Brazilian footballer
 - Enrique Tovar Ávalos, Mexican film director
 - Fernando Horácio Ávalos (born 1978), Argentine footballer
 - José Vicente Rangel Ávalos, the mayor of Sucre Municipality in Venezuela
 - Juan de Ávalos (1911-2006), Spanish sculptor
 - John Avalos (born 1964), American politician
 - Johnny Avalos (born 1986), American serial killer
 - Jorge Ramos Ávalos (born 1958), Mexican-American journalist and author.
 
- Luis Ávalos (1946–2014), Cuban actor
 
The d'Avalos were prominent in Renaissance Italy :
- Fernando d'Avalos (1489-1525), 5th Marquess of Pescara, won the Battle of Pavia
 - Alfonso d'Avalos (1502-1546), Italian condottiero and 6th Marquess of Pescara
 - Francesco Ferdinando d'Ávalos (1530–1571), 7th Marquess of Pescara
 
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