DOS 386 or DOS/386 may refer to:
- Concurrent DOS 386, a Digital Research CP/M- and DOS-compatible multiuser multitasking operating system variant since 1987
- FlexOS 386, a Digital Research FlexOS operating system variant since 1987
- PC-MOS/386, a DOS-compatible multiuser, multitasking operating system produced by The Software Link since 1987
See also
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