DSC may refer to:
Academe
- Doctor of Science (D.Sc.)
- District Selection Committee, an entrance exam in India
- Doctor of Surgical Chiropody, superseded in the 1960s by Doctor of Podiatric Medicine
Educational institutions
- Dalton State College, Georgia, United States
- Daytona State College, Florida, United States
- Deep Springs College, California, United States
- Dixie State College, now Utah Tech University, Utah, United States
- Dyal Singh College, Delhi, India
- DSC International School, Hong Kong, China
Science and technology
- DECT Standard Cipher, an encryption algorithm used by wireless telephone systems
- Dice similarity coefficient, a statistical measure
- Differential scanning calorimetry, or the differential scanning calorimeter
- Digital selective calling in marine telecommunications
- Digital setting circles on telescopes
- Digital signal controller, a hybrid microcontroller and digital signal processor
- Digital still camera, a type of camera
- Display Stream Compression, a VESA-developed video compression algorithm
- Distributed source coding, in information theory and communication
- Document Structuring Conventions a PostScript standard
- Doppler shift compensation, in bat echolocation
- Dye-sensitized solar cell
- Dynamic stability control, computerized technology that improves a vehicle's stability
- Desired State Configuration, a feature of Windows PowerShell
- Dynamic susceptibility contrast, a technique in perfusion MRI
- A subarctic climate in Köppen climate classification
Government and military
- Defence Security Corps, of the Indian Army
- Defense Security Command, of the Republic of Korea Armed Forces
- Distinguished Service Cross (Australia), an Australian military award
- Distinguished Service Cross (United Kingdom), a British naval award
- Distinguished Service Cross (United States), an American military award
- United States District Court for the District of South Carolina
Media and entertainment
- Daily Source Code, a podcast by Adam Curry
- Dallas Symphony Chorus, an American choir
- Dave, Shelly, and Chainsaw, a morning radio show in the San Diego, California area
- DeepSouthCon, a science fiction convention in the southern United States
- Detective Shelf Collection, a fictional detective licence group in the light novel series Danganronpa: Kirigiri
- Dutch Swing College Band, a Dutch jazz ensemble
- Star Trek: Discovery, an American science fiction television series
Sport
- Delbrücker SC, a German association football club from Delbrück, North Rhine-Westphalia
- Deep South Conference, a defunct NCAA athletic conference
- Dresdner SC, a German multisport club from Dresden, Saxony
- Dubai Sports City, a multi-venue sports complex in Dubai, United Arab Emirates
- U.S. Postal Service Pro Cycling Team, an American professional road bicycle racing team
Other uses
- Directory of Social Change, a British charity
- Down Syndrome Centre, a registered charity in Ireland
- Dschang Airport, in Cameroon
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