Dominic Burke (c. 1603 – 1649) was an Irish Dominican priest and political agent.
Dominic or Dominick Burke may also refer to:
- Dominic Burke (bishop) (died 1704), Irish Roman Catholic Bishop of Elphin from 1671 to 1704
- Dominick Burke (died 1747), Irish politician
- Dominic Burke (businessman) (born 1958), British businessman
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