The quarterfinals were two-legged ties determined on aggregate score. The first legs was played on March 23. All return legs were played on March 30. The group winner in each tie, listed as "Team #1", hosted the second leg.

Team #1 Agg. Team #2 1st leg 2nd leg
UNICS Kazan Russia169–161Italy Pepsi Caserta90–8479-77
BC Budivelnyk Ukraine129–144Spain Cajasol49–6780-77
Asefa Estudiantes Spain153–171Croatia Cedevita Zagreb81–9072-81
Benetton Basket Bwin Italy150–128Germany BG Göttingen66–6684-62

Game 1

23 March 2011
18:00
Cedevita Zagreb Croatia 90–81 Spain Asefa Estudiantes
Scoring by quarter: 21–33, 26–16, 29–12, 14–20
Pts: Rudež 21
Rebs: Petrović 8
Asts: Draper 5		 Pts: Caner-Medley 19
Rebs: Caner-Medley 11
Asts: Granger 4
Dražen Petrović Basketball Hall, Zagreb
Attendance: 5,200
Referees: Paolo Taurino (ITA), Eddie Viator (FRA), Damir Javor (SLO)
23 March 2011
19:30
BG Göttingen Germany 66–66 Italy Benetton Basket Bwin
Scoring by quarter: 21–15, 20–17, 9–19, 16–15
Pts: Scott 15
Rebs: Scott 8
Asts: Meacham 3		 Pts: Gentile 22
Rebs: Brunner 10
Asts: Marković 6
Lokhalle, Göttingen
Attendance: 3,250
Referees: Jose Ramon Garcia Ortiz (ESP), Luis Lopes (POR), Oscar Perea (ESP)
23 March 2011
20:00
Pepsi Caserta Italy 84–90 Russia UNICS Kazan
Scoring by quarter: 18–22, 26–24, 16–15, 24–29
Pts: Williams 22
Rebs: Jones 9
Asts: Bowers 4		 Pts: Veremeenko 30
Rebs: Veremeenko 12
Asts: Popović 6
PalaMaggiò, Caserta
Attendance: 4,963
Referees: Spiros Gkontas (GRE), Robert Vyklicky (CZE), Radomir Vojinovic (MNE)
23 March 2011
20:00
Cajasol Spain 67–49 Ukraine BC Budivelnyk
Scoring by quarter: 14–16, 16–8, 13–13, 24–12
Pts: Urtasun 15
Rebs: Kirksay 8
Asts: Urtasun, Bullock 3		 Pts: Keys, Wilson 11
Rebs: Wilson 6
Asts: Anisimov 3
Palacio Municipal San Pablo, Seville
Attendance: 7,500
Referees: Fabio Facchini (ITA), Gianluca Mattioli (ITA), Joseph Bissang (FRA)

Game 2

30 March 2011
18:30
UNICS Kazan Russia 79–77 Italy Pepsi Caserta
Scoring by quarter: 26–17, 20–18, 17–24, 16–18
Pts: Lampe 31
Rebs: Lampe 16
Asts: Popović 6		 Pts: Jones 23
Rebs: Jones 10
Asts: Di Bella 6
Basket Hall Arena, Kazan
Attendance: 2,500
Referees: Jakub Zamojski (POL), Murat Biricik (TUR), Tomas Jasevicius (LTU)
30 March 2011
18:30
BC Budivelnyk Ukraine 80–77 Spain Cajasol
Scoring by quarter: 23–22, 17–17, 14–17, 26–21
Pts: Ikovlev, Spencer 12
Rebs: Betts 10
Asts: Keys 4		 Pts: Urtasun 15
Rebs: Triguero 8
Asts: Bullock, Ivanov 3
Palace of Sports, Kyiv
Attendance: 3,450
Referees: Sreten Radovic (CRO), Milivoje Jovcic (SRB), Sergey Mikhaylov (RUS)
30 March 2011
20:30
Asefa Estudiantes Spain 72–81 Croatia Cedevita Zagreb
Scoring by quarter: 25–26, 17–15, 15–19, 15–21
Pts: Gabriel, Jasen 12
Rebs: Caner-Medley 12
Asts: Granger 3		 Pts: Wright 24
Rebs: Wright 11
Asts: Draper 5
Palacio Vistalegre, Madrid
Attendance: 14,000
Referees: Recep Ankarali (TUR), Paolo Taurino (ITA), Carmelo Paternico (ITA)
30 March 2011
20:30
Benetton Basket Bwin Italy 84–62 Germany BG Göttingen
Scoring by quarter: 25–20, 20–17, 20–13, 19–12
Pts: Smith 22
Rebs: Perić 8
Asts: Marković 10		 Pts: Anderson 25
Rebs: Anderson 7
Asts: Five players 1
Palaverde, Treviso
Attendance: 3,816
Referees: Dubravko Muhvic (CRO), Juan Carlos Garcia Gonzalez (ESP), Nicola Maestre (FRA)
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