Francis Loomis may refer to:
- Francis B. Loomis (1861–1948), 25th United States Assistant Secretary of State
- Francis Loomis (lieutenant governor) (1812–1892), Lieutenant Governor of Connecticut, 1877–1879
- Francis Wheeler Loomis (1889–1976), American scientist
- Francis B. Loomis Jr. (1903–1989), United States Marine Corps general
See also
- Frank Loomis (1896–1971), American athlete
- Loomis (surname)
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