GTM may refer to:
- Guatemala
- Generative topographic map
- Global Traffic Manager, a load balancing module for some F5 Networks appliances
- Golden Triangle Mall, a mall in Denton, Texas
- Google Tag Manager
- Go to market, a strategy to approach the market with a new product or service
- GoToMeeting, online meeting and desktop sharing software
- Graduate Texts in Mathematics, a series of mathematics textbooks published by Springer-Verlag
- Grammar translation method
- Greater Manchester, metropolitan county in England, Chapman code
- Greentech Media, a media and research company that covered the green technology market
- Greystone Technology M, a schema-less transactional database
- Groovin' the Moo, an annual music festival held at various regional centres across Australia during the middle of the year
- Gross Ton Mile, the product of total weight (including the weight of lading cars and locomotives) and the distance moved by a train or other vehicle
- Gross Trailer Mass, the portion of the mass of a fully laden trailer that is carried by the wheels
- GT-M, a Soviet tracked military vehicle
- GT-MU, a command and control variant
- GTM Cars
- GTM Supercar Factory Five Racing
- Large Millimeter Telescope (Spanish: Gran Telescopio Milimétrico), the world's largest millimetric telescope, located in Mexico
- Great Translation Movement, online anti-war movement
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