Greensburg may refer to:

Places

In the United States

• Greensburg, Indiana
• Greensburg, Kansas
• Greensburg, Kentucky
• Greensburg, Louisiana
• Greensburg, Missouri
• Greensburg, Ohio
• Greensburg Township, Putnam County, Ohio
• Greensburg, Pennsylvania
• Greensburg, West Virginia

Other

• "Greensburg", a track on Fetchin Bones' second album, Bad Pumpkin
• Greensburg (TV series) (2008-2010), about the rebuilding of Greensburg (Kansas) after being struck by an EF5 tornado