Itzhak (Hebrew: יצחק) is a Hebrew given name and surname, meaning Isaac. Notable people with the name include:

Given name

• Itzhak Arnon (1909–2005), Israeli agronomist
• Itzhak Bars (born 1943), American theoretical physicist at the University of Southern California
• Itzhak Ben David (1931–2007), Israeli cyclist
• Itzhak Bentov (1923–1979), Czech-born Israeli American scientist, inventor, mystic
• Itzhak Brook (born 1941), Adjunct Professor of Pediatrics and Medicine at Georgetown University School of Medicine
• Itzhak de Laat (born 1994), Dutch short track speed skater
• Itzhak Drucker (born 1947), Israeli football defender
• Itzhak Fintzi (born 1933), Bulgarian film and stage actor
• Itzhak Gilboa (born 1963), Israeli economist
• Itzhak Fisher, vice president at Nielsen Holdings
• Itzhak Katzenelson (1886–1944), Jewish teacher, poet and dramatist
• Itzhak Levanon (born 1944), Israeli ambassador to Egypt from 2009 to 2011
• Isaac Luria, also known as Itzhak Luria (1534–1572), Ottoman Syrian rabbi and mystic
• Itzhak Luria (born 1940), Israeli olympic swimmer
• Itzhak Mamistvalov, Israeli Paralympic swimmer
• Itzhak Nir (born 1940), Israeli Olympic competitive sailor
• Itzhak Nissan, chairman and CEO of Meteor Aerospace Ltd., a privately owned Israeli Defense and Security company that Nissan founded
• Itzhak Perlman (born 1945), Israeli-American violinist, conductor, and pedagogue
• Itzhak Rashkovsky (born 1955), Russian-Israeli violinist and pedagogue
• Itzhak Schneor (1925–2011), Israeli footballer and manager
• Itzhak Shum (born 1948), Israeli footballer and manager
• Itzhak Stern (1901–1969), Polish-Israeli Jewish man who worked for Oskar Schindler and assisted him in his rescue activities
• Itzhak Vissoker (born 1944), Israeli footballer

Surname

• Gil Itzhak (born 1993), Israeli footballer
• Miron Itzhak (born 1953), psychologist
• Ran Itzhak (born 1987), Israeli footballer

See also

• Isaac (name)
• Yitzhak