James or Jim O'Neil may refer to:
- James A. O'Neil (1800–1874), American businessman and politician
- Jim O'Neil (ice hockey) (1913–1997), Canadian professional ice hockey player
- Jim O'Neil (American football), American football defensive coordinator
- James O'Neil, American political candidate; see New Hampshire state elections, 2004
See also
- James O'Neill (disambiguation)
- Jimmy O'Neill (disambiguation)
- James O'Neal (disambiguation)
- Jim O'Neill (disambiguation)
- James Neal (disambiguation)
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