John or Jon Bryant may refer to:

Academia and science

• John B. Bryant (1947–2020), American economist
• John Collins Bryant (1821–1901), American physician, author and college co-founder
• John Harland Bryant (1925–2017), American physician
• John Henry Bryant (1825–1903), medical doctor and member of the Los Angeles Common Council

Arts and entertainment

• John Delavau Bryant (1811–1877), American poet and physician
• John Bryant (harpist) (1832–1926), Welsh harpist
• John Bryant (journalist) (1943–2020), British journalist and marathon founder
• Jon Bryant (born 1986), Canadian singer-songwriter
• John Bryant (actor) (1916–1989) American actor of stage, film, and television

Government and politics

• John Bryant (Oklahoma politician) (c. 1958–2011), American politician
• John Emory Bryant (1836–1900), American politician in Georgia
• John Hope Bryant (born 1966), author, poverty eradication activist
• John R. Bryant, state legislator in North Carolina
• John Wiley Bryant (born 1947), American politician in Texas

Sports

• John Bryant (basketball) (born 1987), American basketball player
• John Bryant (journalist) (1944–2020), British marathon founder
• John Bryant (sailor) (1930–2023), American Olympic sailor
• John Bryant (sport shooter) (1930–2010), Australian Olympic shooter
• Jon Bryant (rugby union) (born 1976), Welsh rugby union player

Others

• John A. Bryant, Australian businessman, former Chairman and CEO of Kellogg Company
• John Richard Bryant (born 1946), bishop of the African Methodist Episcopal Church
• John W. Bryant (born 1949), leader of the Mormon fundamentalist sect Church of Christ Patriarchal