Kirkup is a surname. Notable people with the surname include:

  • Dan Kirkup (born 1988), English footballer
  • James Kirkup (1918–2009), English poet
  • Joe Kirkup (born 1939), English footballer
  • Seymour Kirkup (1788–1880), English painter
  • Toby Kirkup (1972–2020), English actor, writer and television presenter, known for his role as a police sergeant on Peaky Blinders
  • Zak Kirkup (born 1987), Australian politician
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