The Ladykillers or Ladykillers may refer to:
- The Ladykillers (1955 film), a comedy starring Alec Guinness
- The Ladykillers (2004 film), a remake featuring Tom Hanks
- The Ladykillers (play), a 2011 stage adaptation of the 1955 film
- Ladykillers (film), an unrelated 1988 made-for-TV movie
- National Lampoon's Lady Killers, a 2003 comedy film
- "Ladykillers" (song), a song from the album Lovelife by Lush
- Ladykillers, a 1980–81 Granada Television television series on famous historical murder cases involving women
See also
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