Layne is both a surname and a given name. Notable people with the name include:

Surname:

• Bobby Layne (1926–1986), American football player
• David Layne (born 1939), British soccer player for Sheffield Wednesday
• Jerry Layne (born 1958), Major League Baseball umpire
• Justin Layne (born 1998), American football player
• Kenny Layne (born 1981), Professional wrestler
• Lancelot Layne (died 1990), Trinidadian rapper
• Marcia Layne, British playwright
• Oscar Willis Layne (1918–2016), Panamanian cyclist
• Raheem Layne (born 1999), American football player
• Shontelle Layne (born 1985), Barbadian singer
• Tamrat Layne (born 1995), Ethiopian politician

Given name:

• Layne Abeley, character from Lisi Harrison's The Clique Series.
• Layne Beachley, seven time women's surf World Champion
• Layne Flack, poker professional
• Layne Redmond. American drummer, writer and teacher
• Layne Staley, lead singer of Alice in Chains
• Stacy Layne Matthews, American drag queen

See also

• "Arnold Layne", song by Pink Floyd