Leopold Rügheimer (May 5, 1850 – May 24, 1917) was a notable German chemist whose name is connected to the Staedel-Rugheimer pyrazine synthesis, a reaction that was discovered by himself and Wilhelm Staedel. Rügheimer was born in Walldorf (near Meiningen) in 1850 as the son of a merchant. He studied at the universities of Leipzig, Würzburg and Tübingen. He died in Kiel in 1917 after a successful academic career.
Career
Rügheimer's professional career:
| 1873 | Promotion at the University of Tübingen |
| 1875 | Assistant at the Chemical Institute of Leiden University |
| 1877 | Assistant at the Chemical Institute of the University of Kiel |
| 1889 | Position as Professor ordinarius or physical and pharmaceutical chemistry at the university of Kiel |
Scientific contributions:
- Published an article together with Wilhelm Staedel concerning the synthesis of pyrazines by reacting α-haloketones with ammonia. This procedure is now known as the Staedel-Rugheimer pyrazine synthesis.
- First synthesis of tropic acid in 1880, together with Albert Ladenburg.
- First synthesis of piperine (1882).
See also
References
- W Pötsch. Lexikon bedeutender Chemiker (VEB Bibliographisches Institut Leipzig, 1988) (ISBN 978-3-323-00185-5)
- E von Lippmann. Zeittafeln zur Geschichte der organischen Chemie (Julius Springer, 1921)
- A J Humphrey, D O'Hagan. Tropane alkaloid biosynthesis. A century old problem unresolved. Nat. Prod. Rep. 18 (2001) 494-502 (doi:10.1039/b001713m)
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