Loughton is a surname. Notable people with the surname include:
- Alex Loughton (born 1983), Australian basketball player
- John Loughton (born 1987), Scottish political activist and celebrity TV star
- Tim Loughton (born 1962), British Conservative MP since 1997
- William Loughton Smith (1758–1812), US lawyer and member of the House of Representatives from 1789 to 1797
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