MacPherson or Macpherson is a surname, meaning "son of the parson" in Scottish Gaelic. Notable people with the surname include:
In sports
- Archie Macpherson (born 1937), Scottish football commentator
 - Bruce MacPherson (field hockey), Canadian field hockey player
 - Bryden Macpherson, Australian amateur golfer
 - Duncan MacPherson, ice hockey player
 - Gus MacPherson, Scottish footballer
 - Jeff MacPherson, driver in the CART Championship Car series
 - Michelle MacPherson, Canadian swimmer
 
In politics
- Ben Macpherson (politician), Scottish politician
 - C. B. Macpherson, Canadian academic
 - Dean Macpherson, South African politician
 - Hector Macpherson, Sr. (1875–1970), Canadian-American agricultural economics professor and politician
 - Hector Macpherson, Jr. (1918–2015), American farmer and politician
 - James Ian Macpherson, British lawyer and politician
 - John Alexander MacPherson, Australian politician
 - John MacPherson (governor of India), Scottish administrator in India
 - John Thomas Macpherson (1872–1921), English politician
 - Malcolm MacPherson (1904–1971), Scottish politician
 - Murdoch MacPherson, Canadian politician
 - Niall Macpherson, 1st Baron Drumalbyn, Scottish politician
 - Nicholas Macpherson, British civil servant
 - Thomas Macpherson, 1st Baron Macpherson of Drumochter (1888–1965), Scottish politician
 
In music
- Ben Macpherson, Australian musician
 - Christina Macpherson, Australian behind Waltzing Matilda
 - Fraser MacPherson, Canadian jazz musician
 - Greg MacPherson, Canadian singer-songwriter
 - Graham MacPherson, better known as Suggs, the lead singer of the English band Madness
 - Jim Macpherson, United States percussionist
 - Linda Lizotte-MacPherson, Canadian public servant
 - Sandy MacPherson, Canadian theatre organist
 - Donald Macpherson BEM was a Scottish bagpipe player, and one of the most successful competitive solo pipers of all time
 
In literature
- James Alan McPherson, American essayist
 - James Macpherson, Scottish poet
 - Jay Macpherson, Canadian poet
 
In show business and news
- Daniel MacPherson, Australian actor and television presenter
 - Don Macpherson, Canadian journalist
 - Duncan Macpherson, Canadian editorial cartoonist
 - Elle Macpherson, Australian supermodel and actress
 - Gordon Macpherson, Founder of Macpherson Menswear – Palmerston North, New Zealand.
 - Hector Macpherson (1851–1924), Scottish journalist and writer
 - Malcolm MacPherson (1943–2009), American journalist and author
 - Myra MacPherson, American journalist and author
 - Richard MacPherson, American actor
 
Others
- Alexander Macpherson, English architect
 - Cluny MacPherson, Newfoundland medical doctor and inventor of the gas mask
 - Colin MacPherson, Scottish Roman Catholic Bishop of Argyll and the Isles from 1968 to 1990
 - Donald Macpherson (disambiguation), several people
 - Earle S. MacPherson, the Ford engineer who developed the MacPherson strut in the 1940s
 - Ewen MacPherson of Cluny, Scottish Jacobite
 - Fiona Macpherson, FRSE, MAE, Scottish Professor of Philosophy and Director of the Centre for the Study of Perceptual Experience, University of Glasgow
 - Hector Macpherson (astronomer) (1888–1956), Scottish clergyman and astronomer, son of Hector C. Macpherson
 - Ian MacPherson, Canadian historian
 - Jamie Macpherson, Scottish outlaw, famed for his lament
 - John Macferson, early 18th-century English pirate
 - Sir Macpherson Robertson, Australian philanthropist and entrepreneur
 - Robert Macpherson (disambiguation), multiple people
 - Colonel Ronald MacPherson or Ranald MacPherson (1817–1869), architect and colonial administrator
 - Colonel Tommy Macpherson, British army officer
 - Sir William Macpherson, High Court Judge in England
 
Fictional characters
- Anya MacPherson, fictional character in Degrassi: The Next Generation
 - Christine "Lady Bird" McPherson, protagonist of Lady Bird
 
See also
- Clan Macpherson, a Scottish clan
 - The Macpherson Report, into the death of Black British teenage Stephen Lawrence
 - MacPherson v. Buick Motor Co.
 - MacPherson strut, a car suspension system
 - MacPherson, Singapore
 - Macpherson Stadium (disambiguation)
 - McPherson (disambiguation)
 
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