The Malonate Uptake (MatC) family (TC# 2.A.101) is a constituent of the ion transporter (IT) superfamily.[1][2][3] It consists of proteins from Gram-negative and Gram-positive bacteria (e.g., Xanthomonas, Rhizobium and Streptomyces species), simple eukaryotes (e.g., Chlamydomonas reinhardtii) and archaea (e.g., Methanococcus jannaschii). The proteins are of about 450 amino acyl residues in length with 12-14 putative transmembrane segments (TMSs). Closest functionally-characterized homologues are in the DASS (TC #2.A.47) family. One member of this family is a putative malonate transporter (MatC of Rhizobium leguminosarum bv trifolii, TC# 2.A.101.1.2).[4]

See also

Further reading

  • Chen, Wei Ning; Tan, Kee Yang (2013). "Malonate uptake and metabolism in Saccharomyces cerevisiae". Applied Biochemistry and Biotechnology. 171 (1): 44–62. doi:10.1007/s12010-013-0334-8. PMID 23813405. S2CID 21408607.
  • Schaffitzel, Christiane; Berg, Michael; Dimroth, Peter; Pos, Klaas M (1998). "Identification of an Na+-Dependent Malonate Transporter of Malonomonas rubra and Its Dependence on Two Separate Genes". Journal of Bacteriology. 180 (10): 2689–2693. doi:10.1128/JB.180.10.2689-2693.1998. PMC 107221. PMID 9573154.

References

  1. ↑ Lolkema, Juke S.; Slotboom, Dirk Jan (2003-04-11). "Classification of 29 families of secondary transport proteins into a single structural class using hydropathy profile analysis" (PDF). Journal of Molecular Biology. 327 (5): 901–909. doi:10.1016/s0022-2836(03)00214-6. ISSN 0022-2836. PMID 12662917.
  2. ↑ Prakash, Shraddha; Cooper, Garret; Singhi, Soumya; Saier, Milton H. (2003-12-03). "The ion transporter superfamily". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1618 (1): 79–92. doi:10.1016/j.bbamem.2003.10.010. ISSN 0006-3002. PMID 14643936.
  3. ↑ Rabus, R.; Jack, D. L.; Kelly, D. J.; Saier, M. H. (1999-12-01). "TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters". Microbiology. 145 (12): 3431–3445. doi:10.1099/00221287-145-12-3431. ISSN 1350-0872. PMID 10627041.
  4. ↑ "2.A.101 The Malonate Uptake (MatC) Family (Formerly UIT1)". Transporter Classification Database. Retrieved 2016-03-03.

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