Manos (Greek: Μάνος) is both a surname and a given name. Notable people with the name include:

Surname:

• Aspasia Manos (1896–1972), the Greek wife of Alexander I
• John Michael Manos, (1922–2006), U.S. federal judge
• Stefanos Manos (born 1939), Greek politician

Given name:

• Manos Hadjidakis (1925–1994), Greek composer
• Manos Katrakis (1908–1984), Greek actor
• Manos Loïzos (1937–1982), Greek songwriter
• Manos Papayiannis (born 1966), Greek actor