Marcantonio or Marc'Antonio is a masculine Italian given name. Notable people with the name include:

• Marcantonio Amulio (1506–1572), Venetian diplomat and cardinal
• Marcantonio Barbarigo (1640–1706), Italian cardinal
• Marcantonio Barbaro (1518–1595), Italian diplomat
• Marcantonio Bellavia, 17th-century Italian painter
• Marcantonio Bobba (died 1575), Italian Roman Catholic bishop and cardinal
• Marcantonio Borghese, 5th Prince of Sulmona (1730–1800)
• Marcantonio Bragadin (disambiguation), multiple people
• Marcantonio Campeggi (died 1553), Italian Roman Catholic bishop
• Marcantonio Canini (1622–1669), Italian painter and sculptor
• Marcantonio Chiarini (c. 1652 – 1730), Italian Baroque painter
• Marcantonio Colonna (disambiguation), multiple people
• Marcantonio Dal Re (1697–1766), Italian engraver and publisher
• Marcantonio De Beaumont-Bonelli, Italian sailor
• Marcantonio della Torre (1481–1511), Italian anatomist
• Marcantonio Dordi (1598–1663), Italian painter
• Marcantonio Durando (1801–1880), Italian Roman Catholic priest
• Marcantonio Flaminio (died 1550), Italian poet
• Marcantonio Franceschini (1648–1729), Italian Baroque painter
• Marcantonio Genovesi (died 1624), Italian Roman Catholic bishop
• Marcantonio Genua (1491–1563), Italian philosopher
• Marcantonio Giustinian (1619–1688), Doge of Venice
• Marcantonio Gozzadini (1574–1623), Italian cardinal
• Marc'Antonio Ingegneri, 16th-century Italian Renaissance composer
• Marcantonio Maffei (1521–1583), Italian Roman Catholic bishop and cardinal
• Marcantonio Marcolini (1721–1782), Italian Roman Catholic bishop and cardinal
• Marc'Antonio Mazzoleni (died 1632), Italian engineer
• Marcantonio Memmo (1536–1615), Doge of Venice
• Marcantonio Michiel (1484–1552), Venetian noble
• Marcantonio Negri (died 1624), Italian composer, singer and music director
• Marc'Antonio Pasqualini (1614–1691), Italian opera singer
• Marcantonio Pellini (1659–1760), Italian painter
• Marcantonio Raimondi, 16th-century Italian engraver
• Marcantonio Riverditi (died 1744), Italian Baroque painter
• Marcantonio Trivisan, Doge of Venice
• Marc'Antonio Verità (died 1650), Roman Catholic bishop
• Marc'Antonio Ziani (c. 1653 – 1715), Italian composer
• Marcantonio Zimara, 16th-century Italian philosopher
• Marc'Antonio Zondadari (1658–1722), Italian noble