Monroe is a masculine given name which may refer to:

People

• Monroe Althouse (1853–1924), American composer and bandmaster
• Monroe Baker (1821 or 1823–?), American politician, one of the first, possibly the first, African-American mayors in the United States
• Monroe Beardsley (1915–1985), American philosopher
• Monroe D. Donsker (1924–1991), American mathematician and a professor
• Monroe Evans (fl. 1966–1969), first Jewish mayor of Fayetteville, North Carolina, United States
• Monroe Hayward (1840–1899), American politician and senator
• Monroe Heath (1827–1894), American politician, mayor of Chicago, Illinois, United States
• Monroe Fein (1923–1982), US Navy lieutenant and captain of the Altalena in the 1948 Altalena Affair
• Monroe Karmin (1929–1999), American Pulitzer Prize-winning journalist
• Monroe Henry Kulp (1858–1911), American politician
• Monroe Alpheus Majors (1864–1960), American physician, writer and civil rights activist
• Monroe G. McKay (1928–2020), United States circuit judge
• Monroe Morton (1856–1919), African-American businessperson and postmaster
• Monroe Jackson Rathbone II (1900–1976), American businessman, chairman, president, and CEO of Standard Oil of New Jersey
• Monroe Minor Redden (1901–1987), American politician
• Monroe Rosenfeld (c. 1861–1918), American songwriter and journalist
• Monroe M. Shipe (1847–1924), American real estate developer and streetcar network operator

Fictional characters

• Monroe Ficus, in the American sitcom Too Close for Comfort
• Monroe, in the American television series Grimm
• Monroe, in the American animated television series The Life and Times of Juniper Lee (2005–2007)
• Monroe, main character of William Wray's comic strip Monroe, published in Mad magazine