Moscona is a surname. Notable people with the surname include:
- Anne Moscona, American pediatrician and virologist, daughter of Aron
- Aron Moscona (1921–2009), Israeli-born American developmental biologist, father of Anne
- Myriam Moscona (born 1955), Mexican writer
- Nicola Moscona (1907–1975), Greek operatic bass
Moscona may also refer to:
- Moscona (horse), a Chilean racehorse
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